Indian J Physiol Pharmacol. Oct;45(4) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Singh B(1). Request PDF on ResearchGate | Hepatoprotective activity of Eclipta alba Hassk. against paracetamol induced hepatocellular damage in mice | The effect of. The hepatoprotective activity of different extracts of whole plant Eclipta alba was investigated against CCl4 induced hepatic damage inmale albino rat.

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Indian J Physiol Pharmacol. The hepatotoxic agent CCl4 was used to activtiy liver toxicity and silymarin was used as a control drug. A preliminary phytochemical screening was carried out for the extracts employing the standard procedure to reveal the presene of alkaloids, steroids, terpenes, flavonoid, saponins, tennins, glycosides, carbohydrates and proteins. Hepatoprotective activity of Cleome viscosa Linn. Hence, the study was conducted to elucidate the hepatoprotective activity of aqueous extract of hepatoptotective medicinal plant Eclipta alba against carbon tetrachloride CCl4 induced toxicity in male albino rats.

Regarding ALP the value remained to be a bit higher as aactivity to the control group and Silymerin treatment. Copy the following to cite this article: They were given a week time to get acclimatized with the laboratory conditions. KSaxena R. The level of total protein was found to be at normal level after the treatment.

In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

This plant showed antihepatotoxic activity in assays using CCl4 galactosomine and phalloidin — induced cytotoxicity in cultured rat hepatocytes Wagner et al. The observations of these dose, clearly indicat the involvement of heptoprotective active principles in Eclipta alba. Chandra T, Activityy J. Rats were divided in to six groups of 6 rats each as follows. Evaluation of hepatoprotective activity of hepatoprotecfive extracts of leaves of Basella alba in albino rats.


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In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

Protective effect of picroliv, active constituent of Picrorhiza kurrooa, against oxytetracycline induced hepatic damage. Liver homogenates were also subjected to various biochemical estimation. However, the dose adjustments may be necessary to optimize the similar hepatoprotective efficacy in clinical settings. Thus, it is quite clear that, total hepwtoprotective, cholesterol and phospholipids were found to be increased against the control group Ist.

April 04, Published online on: J Complement Integr Med.

Total biochemical parameters was recorded in the present study. The extractive yield were found to be All the group were given fresh food daily at Hassk has been widely used in India for the traditional treatment of liver disorders Chopra et al. Effects of silymarin nanoemulsion against carbon tetrachloride-induced hepatic damage.

Mehra and Handa, The protective effect of Eclipta alba on carbon tetrachloride-induced acute liver damage. User Username Password Remember me.

The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4| Abstract

Rest parameters were found to be all most normal level when three different doges of the compound of the Eclipta alba were given to the CCl4 induced hepatotoxic rat. Suresh Kumar hepatoprotecitve Mishra have also reported hepatoprotective effect of Pergularia demia ethanol extract.


Evaluation of hepatoprotective activity of Cleome viscosa Linn. This work is licensed under a Creative Commons Attribution 4. Indian herbal medicines in the treatment of liver diseases: Recent advances in herbal hepatoprotectvie for treatment of liver diseases. The phospholipids content in serum registered a significant aactivity that of liver showed a deamination in CCl4 administered group. Shrivastava performed taxonomic identification and the voucher specimen was deposited in the herbarium of our laboratory for future reference vide access no.

The liver tissue was dissected by blotting of the blood washed in saline. Girish C, Pradhan SC.

Keywords Carbon tetrachloride, Hepatoprotective activity, Eclipta alba, Silymarin. They were then mechanically powdered and sieved. Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats. They were fed with pallets of Golden feed, New Delhi.

The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4

Protective effects of silymarin, a milk thistle Silybium marianum derivative on ethanol-induced oxidative stress in evlipta.

Treatment of CCl4 increases the level of total proteincholesterol in the liver.

One-way Analysis of Variance was used for the hpeatoprotective analysis of data. Hepatoprotective activity of Leptadenia reticulata stems against carbon tetrachloride-induced hepatotoxicity in rats. A histopathological study of the liver further suggest the hepatoprotective efficacy of Eclipta alba extracts fig. Biochanin A protects against acute carbon tetrachloride-induced hepatotoxicity in rats. Biomed Pharmacol J ;1 1.