The electroretinogram (ERG) is a diagnostic test that measures the . The multifocal ERG (mfERG) simultaneously measures local retinal. Multifocal electroretinography (mfERG) is an objective, noninvasive examination for the assessment of visual function. It enables the stimulation. Abstract. AIMS To describe the topography of multifocal electroretinograms ( ERGs) and to explore its diagnostic value in patients with Stargardt’s macular.

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The perifoveal responses are diminished significantly. Transiently decreased a- and b-wave amplitudes under both photopic and scotopic conditions with recovery after 24 hours.

For the presentation of visible stimulus, some suitable CRT monitors are available but most systems have adopted the use of flat-panel liquid crystal displays LCD. A study [6] by Nasser et al.

A variety of techniques have been described in the literature for recording fERGs. Almost as important, mfERGs provide psychophysical evidence to continue drug in those patients who have multifocsl changes in visual field testing. Flash ERGs performed on a light adapted eye will reflect the activity of the cone system. Normal ERG in the absence of peripheral retinal neovascularization, reduced amplitudes of ERG components when peripheral retinal neovascularization is present.

Multifocal ERG in Practice

Implications for the Treatment of Chronic Conditions …. We find that the pericentral loss pattern See Figure 2 is most specific to hydroxychloroquine toxicity. Multifocal ERG thus offers a valuable tool for making this distinction. Enroll in the Residents and Fellows contest. Most manufacturers provide specialty protocols or a number of analysis and recording approaches and there are many potential benefits to taking a flexible approach to protocol selection.

Find a Job Post a Job. When interpreting mfERG results, it is important to view both the 2D individual wave tracings and the 3D color representations. During a recording, the patient’s eyes are exposed to standardized stimuli and the resulting signal is displayed showing the time course of the signal’s amplitude voltage. Protocol text Select a room with little electrical interference.


Dark adapted Oscillatory potentials: The electroretinogram can be elicited by different kinds of stimulation: Page Discussion View form View source History. Electrorretinogdama result illustrates the power of mfERG in differential diagnosis.

Correlatively, a normal multifocal ERG can help exclude Stargardt’s disease. The 3-D array confirms the severe loss in the superior visual field consistent with previous branch artery occlusion.

On the other hand, most OMD patients had slight but significant prolonged latencies across the whole tested field. To make it easier for the person being tested, the recording is divided into short segments of 15 to 30 seconds.

Always place subjects in the same position and use the same room lighting electrotretinograma every subject. Residents and Fellows contest rules International Ophthalmologists contest rules.

By using this site, you agree to the Terms of Use and Privacy Policy. The computer cross-correlates the fluctuations in voltage with each change in the m-sequence.

Multifocal Electroretinograms

This new technology was developed by Erich Sutter in the early s and involves powerful computers and high —intensity display monitors. The ERG is composed of electrical potentials contributed by different cell types within the retina, and the stimulus conditions flash or pattern stimulus, whether a background light is present, and the colors of the stimulus and background can elicit stronger response from certain components.

While the subject views the display, a single continuous electroretinogram recording is obtained. Initially decreased oscillatory potentials, later stages involve reduced a- and rlectrorretinograma amplitudes.

Miltifocal a-wave amplitude is measured from baseline to the trough of the a-wave. Multifocal electroretinograms are a mathematical average of an approximation of a b-wave. Multifocal ERGs superimposed on Humphrey visual field showing agreement with field loss.


By contrast, Stargardt’s disease and cone dystrophies show conspicuous reduction in mfERGs in the central macular, where cones dominate. Although it is not known for certain, it is suspected that OPs are generated from the amacrine cells located in the inner retina. The focal ERG fERG; also known as the foveal ERG is used primarily to measure the functional integrity of the fovea and is electrorretniograma useful in providing information in diseases limited to the macula. In healthy eyes, this peak is generated by the cells in the fovea.

In addition, the waveforms rarely return to normal even when the patient notes “normal” vision. The mfERG of patients with retinopathy can be altered in many ways including generalized depression of the mfERG, loss of the central peak waveform, as well as a pericentral loss.

Electroretinography – Wikipedia

You will only be able to see the first 20 seconds. In our lab, we record the ERG with an electrode embedded within a contact lens. The produces multiple ERG recordings reflecting the retinal response of each of the corresponding stimulated area. P50 evaluates the macular function. In our practice, such altitudinal electroorretinograma can sometimes be difficult to distinguish from ischemic optic neuropathy.

Extent of reduced a- and b-wave amplitudes depends on extent of fundus pigmentary changes; longer duration of dark-adaptation may be necessary for scotopic amplitudes to reach normal values.

This wave reflects the hyperpolarization of the photoreceptors due to closure of sodium ion channels in the outer-segment membrane.

The convention is for recording electrode touching cornea or sclera to be positive pole, which produces signal with b-wave up.