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The remaining hits were clustered using MCL with default parameters. Therefore, how the correct direct repeats for recombination are chosen by the recombinase is an open question.
This phenomenon is viiii pronounced under periods of stably stratified warm water conditions when its gas vesicles provide buoyancy leading to the formation of large surface scums in the absence of mixing.
Buikema WJ, Haselkorn R Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions.
Similar proteins, SusA nsp and susB nsp were also found.
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Both uptake and bidirectional hydrogenase gene clusters possess genes for a putative endoprotease, HupW nsp and HoxW nspprocessing the large subunits HupL genes nsp and nsp and HoxH nsprespectively.
TSS are indicated by blue arrows and the number of cDNA reads associated with them are given as approximation for their activity. Magellan is an independent energy company engaged in the exploration, development, production, and sale of crude oil and natural gas from currently held assets in the United States, Australia, and the United Kingdom. This is especially relevant here since biologically available dissolved inorganic and organic phosphorus forms appear critical for N.
For sequence analysis, cDNA libraries were constructed vertis Biotechnologie AG, Germany and analysed on an Illumina sequencer as previously described . Toxic cyanobacterial blooms in aquatic ecosystems are a world-wide problem, which are predicted to increase according to the present scenarios of climate change .
Iron III dicitrate transport system, periplasmic binding proteins. The sequence of Chlorobium tepidum TLS served as outgroup. Related gene clusters if present in the database are shown with their gene annotations and strain names above each gene cluster.
The genome was sequenced using a combination of Sanger and sequencing platforms. The securities described herein have not been registered under the U. Further bioinformatic evidence suggestive of the critical nature of phosphorus in the biology of N. A closer inspection revealed that Nsp possesses a PsaL domain in this additional segment and that nine transmembrane regions are predicted for the PsbC-PsaL hybrid protein SI, Fig. Wang H, Fewer DP, Sivonen K Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria.
Thus, the genetic information required for the generation of these secondary metabolites takes a substantial part of the genomic coding capacity.
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Nat Chem Biol 4: It should be stressed that the multiple TSS in Anabaena PCC were detected by the same approach in the absence of combined nitrogen  as used here for N.
Transcriptional organization around the isiA, isiB and psbC -like gene cluster. A functional class of similar size within this top group of gTSS drives the transcription of translation-related genes for ribosomal proteins S14, S16, L19, L32 and L35the DnaJ chaperone, or translation factor IF3.
However, ArsC encoding arsenate reductase appears to be lacking in the N. This arrangement is almost exactly conserved 50118 N. One of the genes in this category encodes a CP12 protein Table 2. The cyanobactin gene cluster was identified using sequences from the patellamide gene cluster as a query in BLASTp searches. These genes are linked vii nsp the first gene in a putative operon with mts1 and mts2 that encodes for a glycogen de-branching enzyme, making the precursor glycogen for trehalose synthesis accessible.
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