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A subsequent strand-specific transcriptome analysis identified more than 6, putative transcriptional rgr sites TSS. Wang H, Fewer DP, Sivonen K Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria.

Stal LJ Is the distribution of nitrogen-fixing cyanobacteria in the oceans related to temperature? Nierzwicki-Bauer SA, Curtis SE, Haselkorn R Cotranscription of genes encoding the small and large subunits of ribulose-1,5-bisphosphate carboxylase in the cyanobacterium Anabaena A review of recent evidence on the effects of enrichment.

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The remaining hits were clustered using MCL with default parameters. In order to use the potential dr this N.

MIT only 2 of 18 Prochlorococcus genomes currently available possess this cluster and this was concomitant with the ability of this strain to utilise phosphite as sole phosphorus source []. Statements in this press release that are not historical in nature are intended to be, and are hereby identified as, forward-looking statements for purposes of the Private Securities Litigation Reform Act of Appl Environ Microbiol This genome analysis suggests that N.


The two ORFs on the N.

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Moffitt MC, Neilan BA Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins. TonB-dependent receptor; Outer membrane Ferrichrome receptor.

Selected proteins of heterocyst differentiation, pattern formation and nitrogen assimilation in N. The direct repeated sequences from both nifD and hupL elements are present 518 once on the genome of N.

Three different peptide families, cyanobactins [][]microviridins [][] and lantipeptides prochlorosins [] have been described and differ substantially in their respective amino acid functionalities and mode of macrocyclization.

Question marks indicate domains with unclear substrate specificities. These genes are located downstream from hupL and hoxH, and in the case of the uptake hydrogenase separated from hupL by a small ORF.

A phylogenetic analysis of these proteins shows that one of the proteins from this family nsp clusters with several well characterized IsiA proteins and hence is a distinct IsiA homolog. Orphan TSSs located in intergenic regions led us to predict non-coding RNAs, among them 70 copies of a possible retrotransposon and several potential RNA regulators, some of which are also present in other N2-fixing cyanobacteria.

High phosphorus combined with low to undetectable nitrogen concentrations during the summer season hence low N P ratios are principal factors favouring growth and bloom formation of Nodularia in the stratified Baltic Proper and Gulf of Finland [14]. Ferrichrome-iron receptor, Ferrichrome-iron receptor, TonB-dependent receptor. The nsp gene was found to be highly expressed under our standard cultivation conditions 10 PSU explaining the observed sucrose accumulation in these cells F.


Vintila S, El-Shehawy R Variability in the response of the cyanobacterium Nodularia spumigena to nitrogen supplementation. Nucleic Acids Res The multiple sequence alignment was shortened to a total of positions in the final dataset to include also 16S rRNA sequences from species without a genome sequence.

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Possible carbon dioxide concentrating mechanism protein CcmK. Forward looking statements in this press release speak only viii of the date hereof, and the Company undertakes no obligation to update or revise such statements except as required by securities laws.

All three recombinases contain the highly conserved tetrad R-H-R-Y of the phage integrase family with the catalytically active residue tyrosine, but as was described for Fiii and XisC of Anabaena PCC [95]the histidine is substituted by a tyrosine in N.

The genes for catalytic subunits of uptake hydrogenase, hupS nsp and hupL nsp and nsp, which become fused following heterocyst-specific recombinationare separated by an intergenic stretch that might form a hairpin as has been described for other cyanobacteria [72].

The complete nodularin synthetase nda gene cluster was elucidated from an Australian N. Transcriptional organization around the isiA, sgr and psbC -like gene cluster. PCC sps — sllspp — slr [50].